pH‐Triggered Release and Degradation Mechanism of Layered Double Hydroxides with High Loading Capacity

The loading capacity and strategy of layered double hydroxides (LDHs) determine their suitability for drug delivery applications. In this study, two sizes MgAl-CO3 LDHs are converted into MgAl-NO3 MgAl-Cl by an acid-salt method. influence the size type interlayer anions on studied compared. Here, Methylene Orange (MO) served as anionic structure to capacity. Due strongest anion-exchange NO3− larger distance LDHs, they have impressive high capacities, which make these useful absorbents or carriers. Additionally, pH-dependent release behaviors MO-loaded investigated, dictates both profile maximum release. Above all, based it is found that with agents loaded under mildly acidic environments not its partial dissolution, commonly indicated. This study provides a better understanding process allows incorporation in biomedical-related